Cambrionix have created a USB Hub that is capable of connecting 49 USB devices up to your computer. If you are the type of person who has a ton of USB devices that you could connect up then this product is for you. The hub takes it's power from a standard ATX power supply and allows you to access a number of devices without having to unplug and replug all the time.
I guess to fill up all 49 ports you'll have to either look at buying a ton of cameras and MP3 players or settle for cheaper USB cups, hand and foot warmers and what not as I really think 49 is pushing is a bit too far.
The Cambrionix USB Hub costs £399+VAT with details available here.